5-chloro-1H-indazol-3-yl acetic acid

5-chloro-1H-indazol-3-yl acetic acid - Names and Identifiers

Name	(5-chloro-1H-indazol-3-yl)acetic acid
Synonyms	5-Chloro-1H-3-indazoleacetic acid 5-Chloro-1H-indazole-3-acetic acid 5-CHLOROINDAZOLE-3-CARBOXYLIC ACID 5-chloro-1H-indazol-3-yl acetic acid 1H-indazole-3-acetic acid, 5-chloro- (5-chloro-1H-indazol-3-yl)acetic acid 5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID 2-(5-chloro-1H-indazol-3-yl)acetic acid 2-(5-chloro-2H-indazol-3-yl)acetic acid 5-CHLORO-3-(1H)INDAZOLE CARBOXYLIC ACID
CAS	27328-68-3
InChI	InChI=1/C9H7ClN2O2/c10-5-1-2-7-6(3-5)8(12-11-7)4-9(13)14/h1-3H,4H2,(H,11,12)(H,13,14)

5-chloro-1H-indazol-3-yl acetic acid - Physico-chemical Properties

Molecular Formula	C9H7ClN2O2
Molar Mass	210.62
Density	1.566
Melting Point	approximate 199℃(dec.)
Boling Point	463.9±30.0 °C(Predicted)
Flash Point	234.336°C
Vapor Presure	0mmHg at 25°C
pKa	3.81±0.30(Predicted)
Storage Condition	2-8°C
Refractive Index	1.711
Physical and Chemical Properties	This product is solid, insoluble in water.

5-chloro-1H-indazol-3-yl acetic acid - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
HS Code	29339900

5-chloro-1H-indazol-3-yl acetic acid - Reference Information

use

5-chloro-1H-indazole-3-acetic acid is an intermediate of plant growth regulator indazole.

Production method

The preparation method is based on benzaldehyde as raw material, first chlorinated to produce 3-chlorobenzaldehyde, and then nitrated to obtain 5-chloro-2-nitrobenzaldehyde, and further reacted with malonic acid in the presence of formic acid and ammonium formate to obtain 3-(2-nitro-5-chlorophenyl)-3-aminopropionic acid, then it is reduced with hydrazine hydrate or aluminum powder and cyclized to obtain the product.

Last Update：2024-04-09 15:16:49